The lymphatic system is a linear network of lymphatic vessels and secondary lymphoid organs. STRUCTURE AND FUNCTION OF THE LYMPHATIC SYSTEM In this review, we discuss the current understanding of the development and function of the lymphatic system and human diseases related to the lymphatic system. ![]() Modern molecular, cellular, and genetic approaches as well as the state-of-the-art imaging technologies have allowed true appreciation of the value of the lymphatic system as the other vascular system, no longer secondary to the blood vascular system. However, a series of landmark discoveries in past decades has unraveled much of the mystery of the lymphatic system and yielded a burst of new knowledge in the field of vascular biology and medicine. ![]() Although both systems were initially described by Hippocrates and share so many functional, structural, and anatomical similarities, the two vascular systems have had very different fates in science and medicine: Although the blood vascular system has been intensively and extensively studied for a long time, the lymphatic system, in contrast, has been considered less important, invisible, secondary to the blood vascular system, and thus largely neglected by scientists and clinicians until recent years. The human body has two major circulatory systems: the blood and lymphatic systems.
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